6) Biotransformation of drugs is primarily directed to a) Activate the drug b) Inactivate the drug c) Convert lipid soluble drugs into nonlipid soluble metabolites d) Convert nonlipid soluble drugs into lipid soluble metabolites

The correct answer is c) Convert lipid-soluble drugs into nonlipid-soluble metabolites.<br /><br />Biotransformation, also known as drug metabolism, is the process by which the body converts drugs into different chemical compounds, called metabolites, through enzymatic reactions. The primary goal of biotransformation is to make drugs more water-soluble (nonlipid-soluble) so that they can be easily eliminated from the body through the kidneys and bile.<br /><br />Lipid-soluble drugs are generally more difficult to eliminate from the body because they can accumulate in fatty tissues. By converting these lipid-soluble drugs into nonlipid-soluble metabolites, the body can more efficiently eliminate them from the circulation and reduce their potential for toxicity.<br /><br />While biotransformation can sometimes activate a drug or inactivate it, the primary purpose is to facilitate the elimination of the drug from the body. Therefore, option c) is the most accurate answer.