9. Acet lcholine (ACh) is an important signaling molecule in the nervous system down by the enzyme acetylcho linesteras e (AChE)) in a reaction known as ACh of the following best the effec t AChE has on the hydrolysis of ACh? A . AChE increases the activation energy of ACh hydrolysis ,increasing the rate o B.. AChE increases the activation energy of ACh hydrolysis , decreasing the rate C . AChE decreases the activation energy of ACh hydrolysi s, increasin g the rate c D . AChE decreases the activation energy of ACh hydrolysis decreasing the rate 10.A functional enzyme together with its cofactor is called: A . Holoenzyme B Apoenzyme C . Coenzyme D Prostheric enzyme 11. With regards to the Michaelis -Menten equation a molecule that has the effect Vmax of a reaction upon binding to an enzy me would be called what? A Activator B . Uncompetitiv inhibitor C . Non-competitiv e inhibitor D.. Competitive inhibitor 12 . Which statemen t is true of enzymes? A . Enzymes work independent of substrate concentration. B. The activity of an enzyme might change as pH changes. C . Changes in temperatur e do not affect enzymes. D.. Enzymes catalyze chemica reactions by increasing the activation energy. 13. The active site model (also called the lock and key model) of enzyme-substrat from the induced fit model in which of the following ways? . The induced fit mode holds that the shape of the active site is altered during t substrate binding . The induced fit model holds that the shape of the substrate is irrelevant to enz binding . The induced fit model holds that the shape of the active site is permanently al binding . The induced fit model holds that enzyme.-substrate binding does not take plac active site . What is true of an uncompetitive inhibitor? It binds only to the formed between the enzyme and the substrate It reduces the activity of the enzyme and binds equally well to the enzyme wh already bound the substrate It forms the same products as the substrate. It binds to the active site of the enzyme. It binds with the enzyme in a place other than the active site of the enzyme.

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9. Acet lcholine (ACh) is an important signaling molecule in the nervous system down by the enzyme acetylcho linesteras e (AChE)) in a reaction known as ACh of the following best the effec t AChE has on the hydrolysis of ACh? A . AChE increases the activation energy of ACh hydrolysis ,increasing the rate o B.. AChE increases the activation energy of ACh hydrolysis , decreasing the rate C . AChE decreases the activation energy of ACh hydrolysi s, increasin g the rate c D . AChE decreases the activation energy of ACh hydrolysis decreasing the rate 10.A functional enzyme together with its cofactor is called: A . Holoenzyme B Apoenzyme C . Coenzyme D Prostheric enzyme 11. With regards to the Michaelis -Menten equation a molecule that has the effect Vmax of a reaction upon binding to an enzy me would be called what? A Activator B . Uncompetitiv inhibitor C . Non-competitiv e inhibitor D.. Competitive inhibitor 12 . Which statemen t is true of enzymes? A . Enzymes work independent of substrate concentration. B. The activity of an enzyme might change as pH changes. C . Changes in temperatur e do not affect enzymes. D.. Enzymes catalyze chemica reactions by increasing the activation energy. 13. The active site model (also called the lock and key model) of enzyme-substrat from the induced fit model in which of the following ways? . The induced fit mode holds that the shape of the active site is altered during t substrate binding . The induced fit model holds that the shape of the substrate is irrelevant to enz binding . The induced fit model holds that the shape of the active site is permanently al binding . The induced fit model holds that enzyme.-substrate binding does not take plac active site . What is true of an uncompetitive inhibitor? It binds only to the formed between the enzyme and the substrate It reduces the activity of the enzyme and binds equally well to the enzyme wh already bound the substrate It forms the same products as the substrate. It binds to the active site of the enzyme. It binds with the enzyme in a place other than the active site of the enzyme.

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9. C. AChE decreases the activation energy of ACh hydrolysis, increasing the rate. 10. A. Holoenzyme 11. B. Uncompetitive inhibitor 12. B. The activity of an enzyme might change as pH changes. 13. A. The induced fit model holds that the shape of the active site is altered during substrate binding. 14. B. It reduces the activity of the enzyme and binds equally well to the enzyme whether or not the substrate is already bound.

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