- 7. The active site model (also called the lock and key model)of enzyme-substrat binding differs from the induced fit model in which of the following ways? A. The induced fit model holds that the shape of the substrate is irrelevant to enzyme-substrate binding B. The induced fit model holds that the shape of the active site is altered during the course of substrate binding C. The induced fit model holds that the shape of the active site is permanently altered by substrate binding D. The induced fit model holds that enzyme-substrate binding does not take place at the enzyme's active site 8. Which of the following enzyme types catalyzes the formation of a single bond between two substrates? A. Ligase B. Oxidoreductase C. Isomerase D. Hydrolase 9. Enzymes undergo a decrease in catalytic efficiency in the presence of excess temperature, but can regain this efficiency once temperature returns to normal: this suggests that increased temperature does not disrupt which of the aspects of enzyme structure? A. Peptide bonds B. Van der Waal's forces C. Hydrophobic interactions D. Hydrogen bonds 10. Local conditions can affect the specificity of an enzyme for its substrate, and thus the enzymes catalytic ability:which of the following alterations would most likely not affect an enzyme in this manner? A. Increased temperature B. Increased concentration of H+ C. Increased substrate concentration D. Increased concentration of salts 11. Enzymes catalyze biochemical reactions by altering which of the following quantities associated with the reaction? A. The change in Gibb's free energy Delta G B. The equilibrium constant k_(eq) C. The enthalpy of formation Delta H D. The activation energy E_(a) 12. Potassium cyanide is a poison which combines with cytochrome to prevent binding of oxygen to the enzyme without altering the Km of the reaction with respect to reduced cytochrome C. Which type of inhibition does this represent? A. Noncompetitive inhibition B inhibition produces glucose-phosphate. G-6-P itself can also C. Competitive inhibition
- 2. A. Letter B represents the energy difference between the reactants and products for the uncatalyzed pathway. B. Letter B represents the energy difference between the reactants and products for the catalyzed pathway. C. Letter B represents the activation energy of the uncatalyzed reaction pathway. D. Letter B represents the activation energy of the catalyzed reaction pathway. 3. Pancreatic amylase is a digestive enzyme found in the small intestine. It helps break down large starch molecules later in the digestive process. Pancreatic amylase is unable to break down lipid A. Lipids are too hydrophobic to be broken down by enzymes. B. Lipids are too small to bind to enzymes. C. Enzymes bind only to their specific substrates. D. Enzymes denature in the presence of lipids. 4. Phosphoglucomutase which catalyses the formation of glucose-6 -phosphate from glucose-1- phosphate,is best classified as which of the following enzyme type? A. Oxidoreductase B. Isomerase C. Kinase D. Lyase 5. The active site of an enzyme E which catalyzes a reaction X, is partially denatured:which following quantities associated with X is most likely to be affected by the partial denaturati E compared to the native form of E? A. the rate-constant k B. the boltzmann constant k_(b) C. the heat of reaction Delta H D. the equilibrium constant k_(eq) 6. Which of the following molecules cannot be classified as an enzymatic cofactor? A. Valine B. FAD (Flavine adenine Dinucleotide) C. Mg2+ D. Heme
- a Lecture.Cell membrane potentials () Hodgkin-Haxleymodel (4th from the end Theory discussion A the change of chem cquation. Delta 4_(m)=4_(ar)-4_(in) 4_(out) Gass J=M_(0)+kTlnC+zF4 Theorell equation moastion colation atside Nernst sum T_(m)=0 (compare) nequation Curtents M_(rest)=M_(11)-sqrt (H_(24))=0
- INgo Retrograde amnesia is usually the result of damage to, or dysfunction of which of the following structures? B Hippocampus Subthalamus Hypothalamus Thalamus
- No5 Which brain structure serves as the major controller of the limbic system? 1 Hypothalamus Hippocampus Amygdala Mammillary body Fornix
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