- Variante 3 1. Lequel des micro-organismes suivants ne provoque PAS d'infection respiratoire? b) Strep tococcus pneumoniae c) Mycoplasma pneumoniae d) Haemophilus influenzae 2. L'agent causal le plus fréquent de l'amygdalite aiguë purulente est : a) Streptococcus pyogenes b) Staphylococcus aureus c) Streptococcus pneumoniae d) Haemophilus influenzae 3. Peptostreptococcus est: a) Un anaérobie strict b) Un aérobie c) Un anaérobie facultatif d) Un microaérophile 4. La listériose est causée par : a) Listeria monocytogenes b) Brucella spp. c) Bacillus anthracis d) Francisella tularensis 5. Laquelle des spirochétoses est transmise par une morsure de tique? a) La maladie de Lyme b) La syphilis c) La leptospirose d) La fièvre récurrente 6. Quel entérovirus provoque l'hépatite? a) Virus de l'hépatite A b) Virus Coxsackie c) Virus ECHO d) Poliovirus 7. Le virus qui cause le mégalérythème épidémique appartient à la famille des: a)Parvovirus b)Herpesvirus c) Papillomavirus d) Polyomavirus 8. Une diminution du nombre de lymphocytes CD4+ est caractéristique de quel stade de l'infection par le a) Tous les stades b) Période d'incubation c) Stade des manifestations primaires d) Période de latence 9. Quelle méthode est utilisée pour le diagnostic post-mortem de la rage? a) Recherche des corps de Negri dans le cerveau b) Numération formule sanguine c) Analyse biochimique du sang d) Analyse d'urine 10. Quel type de candidose affecte la muqueuse buccale? a) Candidose oropharyngée b) Candidose vaginale c) Candidose systémique d) Candidose cutanée 11. Quelle méthode est utilisée pour diagnostiquer le paludisme? a) Microscopie d'un frottis sanguin b) PCR c) Tests sérologiques d) Toutes les méthodes mentionnées 12. Mycoplasma pneumoniac provoque : a) Une pneumonie atypique b) Une pneumonie typique c) Une bronchite d) Une trachéite 13. La gangrène gazeuse est le plus souvent causée par : a) Clostridium perfringens b) Clostridium botulinum c) Clostridium tetani d) Bacillus anthracis 14. La tularémie est transmise à l'homme : a) Par des piqüres d'insectes, le contact avec des animaux malades la voie alimentaire b) Par voie aérienne c) Uniquement par les piqüres de moustiques d) Uniquement par contact avec des personnes maladies 15. Le typhus récurrent est transmis : a) Par des piqüres de poux et de tiques b) Par des piqüres de moustiques c) Par voie alimentaire d) Par voie aérienne 16. Quel type d'hépatite est transmis par voie parentérale? a) Hépatite B b) Hépatite A c) Hépatite E d) Tous les types mentionnés 17. Le zona est causé par la réactivation de quel virus? a) Virus varicelle-zona b) Cytomégalovirus c) Virus herpes simplex d) Virus d'Epstein-Barr 18. Quel test est utilisé pour confirmer le diagnostic du VIH?
- 7. To which class of enzymes does chymotrypsin belong? lyases hydrolases ligases isomerases transferases D oxidoreductases
- consumption and name the enzymes involved . Calculate the energy ounding Choose one correct answer: 4. Which of the following gastrointestinal enzymes breaks down starch in the first stage of catabolism? A pepsin B. trypsin C. lipase D. amylase E. sucrase 5. The reactions catalyzed by the pyruvate dehydrogenas e complex occur in the: hondri al matrix B cytoplasm brane space of mitochondria D.lvsosomes E. nucleus 6.Coenzymes participat in the reaction of oxidative decarbox vlation of a-ketoglutarate in the following sequence: A. B. TPP, CoA -SH.NAD FAD, lipoic acid C. TPP, lipoic acid, CoA -SH, FAD , NAD D. NAD, FAD . CoA-SH lipoic acid, TPP E. TPP . CoA-SH,FAD, lipoic acad, NAD 7. The multienzym comple x catalyzes the conversion reaction: A. oxaloacetate + acetyl-CoA - citrate B.succinate →fumarate c isocitrate →a-ketoglutarate D. a-keto glutarate →succinyl-CoA E.malate → ox aloacetate 8. Substrat of microsoma I oxidation is: A.glutamic acid B.arachidonic acid C.aspartic acid D. lactic acid E.malic acid 9. The cvtochrome located on the inner membrane of mitochondria outside the enzyme com plexes is: A. a B. a3 C. c D. C_(1) E.b 10 Mitochondria of brown fat cells differ from the mitochondr ia of other cells in that thev contain: Mito a relatively v high content of components of the respiratory chain and a smal I amount of HY-ATPases A.relatively lower content of components of the respiratory chain and a small amount of H +-ATPases B.relatively high content o component s of the respiratory chain and a large amount of HY-ATPases D.they lack components of the respirator chain E. they lack H +-ATPases 11. Eating confe ctionery and I sweet tea is accompanied by dyspeptic : disorders in a child.such as vomiting and diarrhea.Milk does not cause such a reaction. A cause of this disease is deficiency of enzyme: A. lactase B. maltase C. fructose -1-phosphate aldolase D phosphofructokinase E. sucrase 12 . Iodoacetate ,an inhibitor of sulfhydryl groups , suppresses glycolysis at the level of the enzy me: A.hexokinase B . phosphofructokinase C. aldolase D . phosphoglycerate mutase E. glyceraldehy de phosphate dehy drogenase 13. The redox reaction in glycolysi s is the conversion: A. 3-phosp ohoglycerate → 2-phosp ohoglycerate B 2-phosphoglycerate phosphoenolpyruvate
- Variant 13 I f(10) Define the term "metabolism the main functions of metabolism. Define the concepts of "apabolism" and "catabolism". Give examples of key metabolites. 2 (10). Write the reactions of conversion of fructose -1,6-bisphosphate to glucose Name the enzymes involved and their intracellular location. Specify the role of gluconeogenesi s in the body and the conditions in which its rate increases. 3 (10). Draw a diagram of the glycogen process. Name the enzyme of these reactions an characterize the effect of hormones on the activity of this enzyme. Specify the biological role of glycogen mobilization. Choose one correct answer: 4. The second stage of nutrient catabolism involves the conversion: A. starch-glucose B. fatty acids-acetyl-CoA C. fats - fatty acids + glycerol D. proteins-amino acids E. acetyl-CoA- CO_(2)+H_(2)O 5. The dissociating coenzymes of the a-ketoglutarate dehydrogenase complex are: A. HS-CoA and NAD B. NAD^+ and FAD C. FAD and TDP D. TDP and lipoic acid E. lipoic acid and HS-CoA 6. The multienzyme complex catalyzes the conversion reaction: __ A. oxaloacetate acetyl-CoA - citrate B. succinate - fumarate C. isocitrate -a-ketoglutarate D. a-ketoglutarate -CoA E. malate-oxaloacetate 7. Vitamin B_(1) is a part of the coenzyme: A. NAD B. FAD C. HS-CoA D. TPP E. pyridoxal phosphate 8. Uncoupling of oxidation and phosphorylation in mitochondria indicates that: P_(i) accelerates A. ATP formation from ADP and B. O_(2) consumption stops, but the synthesis of ATP occurs C. ATP synthesis stops.but O_(2) consumption occurs consumption stops D. O_(2) E. decomposition of ATP to ADP and P_(i) accelerates 9. The final electron acceptor in the mitochondrial respiratory chain is: A. molecular oxygen B. atomic oxygen Cu^2+ C. D. cytochrome c E. cytochrome a 10. Microsoma I oxidation is called free oxidation because: A. monooxygenase chain enzymes do not have substrate specificity B. it is not to the phosphorylation of ADP C. in this process., oxygen is incorporated into the oxidized substrate D. cytochrome P450 catalyzes not only hydroxylation, but also other reactions E. hydrogen donors for these reactions are both NADPH and NADH 11. A newborn baby after breastfeeding has dyspeptic disorders (vomiting, diarrhea). This allows to sus lack of one of the following enzymes: A. 1,6-glycosidase B. fructose-1-phosphate aldolase C. phosphofructokinase D. lactase E. maltase
- 6. Competitive inhibitors form covalent bonds with the active center of the enzyme D interact with the allosternic center D interact with the active site of the enzyme a reduce Km reduce Vmax
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